Fimbriae of uropathogenicProteus mirabilis
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چکیده
منابع مشابه
Fimbriae of uropathogenic Proteus mirabilis.
Proteus mirabilis is a common causative agent of cystitis and pyelonephritis in patients with urinary catheters or structural abnormalities of the urinary tract. Several types of fimbriae, which are potentially involved in adhesion to the uroepithelium, can be expressed simultaneously by P. mirabilis: mannose-resistant/Proteus-like (MR/P) fimbriae, P. mirabilis fimbriae (PMF), uroepithelial cel...
متن کاملRole of Proteus mirabilis MR/P fimbriae and flagella in adhesion, cytotoxicity and genotoxicity induction in T24 and Vero cells.
Proteus mirabilis is frequently associated with complicated urinary tract infections (UTI). It is proposed that several virulence factors are associated with P. mirabilis uropathogenicity. The aim of this work was to elucidate genotoxic and cytotoxic effects mediated by MR/P fimbriae and flagella in eukaryotic cells in vitro. Two cell lines (kidney- and bladder-derived) were infected with a cli...
متن کاملProteus mirabilis MR/P fimbriae: molecular cloning, expression, and nucleotide sequence of the major fimbrial subunit gene.
Proteus mirabilis, a cause of serious urinary tract infection and acute pyelonephritis, produces several putative virulence determinants, among them, fimbriae. Principally, two fimbrial types are produced by this species: mannose-resistant/Proteus-like (MR/P) fimbriae and mannose-resistant/Klebsiella-like (MR/K) fimbriae. To isolate MR/P fimbrial gene sequences, a P. mirabilis cosmid library wa...
متن کاملRe: Proteus mirabilis Fimbriae- and Urease-Dependent Clusters Assemble in an Extracellular Niche to Initiate Bladder Stone Formation.
The catheter-associated uropathogenProteus mirabilisfrequently causes urinary stones, but little has been known about the initial stages of bladder colonization and stone formation. We found thatP. mirabilisrapidly invades the bladder urothelium, but generally fails to establish an intracellular niche. Instead, it forms extracellular clusters in the bladder lumen, which form foci of mineral dep...
متن کاملEnterobacterial fimbriae.
Many different species of the family Enterobacteriaceae have been shown to possess fimbrial appendages which emerge from the bacterial cell as straight, rigid organelles distinct from flagella (14). The role of fimbriae (synonym: pili) as adhesins in both enterotoxigenic and uropathogenic isolates of Escherichia coli has been demnonstrated, and thus the identification of such appendages as viru...
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ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2007
ISSN: 0928-8244,1574-695X
DOI: 10.1111/j.1574-695x.2007.00284.x